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The structural models were built using Coot (Emsley et al., 2010) and crystallographic refinement was performed with Phenix.refine (Afonine et al., 2012) including the addition of hydrogens in riding positions and TLS-refinement

Attenuated relationship between cardiac output and oxygen uptake during high-intensity exercise
Curcumin administration has been associated with beneficial changes in gut microbiota composition, leading to improved intestinal barrier function and reduced endotoxin levels that may contribute to liver inflammation through toll-like receptor (TLR) pathways

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