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Inhibition of CYP3A4 activity by its inhibitors, such as macrolide antibiotics (e.g., erythromycin), azoleantifungal agents (e.g., ketoconazole), and protease inhibitors (e.g., ritonavir), may increase plasma concentrations of oxycodone and prolong opioid effects

TZPS bind to the oocyte via Gap-junctions (GJs), which allow low-molecular-weight messages or nutrients to be transferred from cell to cell

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