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From the structural point of view, two copper ions are surrounded by three histidine residues that are responsible for the catalytic activity of tyrosinase (Figure 2) 19

By manipulating these phases to achieve an optimal balance, it may be possible to sustainably harness mitohormesis as a preventative and therapeutic measure for people at risk of, or suffering with, neurodegenerative disorders

The increased ROS production during ferroptosis can also contribute to tumor cell proliferation