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2016, Childhood trauma predicts antidepressant response in adults with major depression: data from the randomized international study to predict optimized treatment for depression. Other risk factors include chronic medical conditions and substance abuse, both of which aggravate or contribute to the development of depression

Don't let the smell turn you off, the right amount mixed into water only has a slightly bitter taste, like lemon water or powdered vinegar

Statements Author contributions XC: Writing original draft, Writing review and editing

Savage, Rosemary A., et al
