l carnitine calcification metabolism in hypertensive heart failure Possible Neuroprotective Effects of l-Carnitine

Dietary LC administration, the pharmacologically active form, is beneficial to patients with uremia and can positively affect neuropathic pain, nerve conduction, and immunological role in diabetic individuals, as well as saving lives in patients with primary carnitine deficiency (Bonomini et al., 2011, Cha, 2008, Ribas et al., 2014)

The hygroscopicity of L-carnitine causes a lack of storability of the solid substance and of simple powder mixtures prepared therefrom, and causes problems such as inadequate flowability during further formulating, processing, and manufacturing of orally administrable dosage forms of pure solid L-carnitine or powdered mixtures containing L-carnitine for use in food, nutritional or dietary supplements for humans or other mammals, animal feed or dietary supplements, or drugs for human or veterinary use

July 21, 2014

Influence of L-carnitine and its derivatives on myocardial metabolism and function in ischemic heart disease and during cardiopulmonary bypass

doi: 10.1038/s41556-019-0287-4 69 HuangWHicksonLEirinAKirklandJLermanL