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Low urinary pH predisposes for uric acid precipitation since the pKa of uric acid is 5.7, therefore the solubility of uric acid decreases with low pH, and thus increasing the risk of kidney stones (8, 44)

In such severe cases, cerebral oedema becomes clinically apparent 12 hours to 4 days after the overdose [18,20,50,87], although CNS depression may be delayed if a slow-release preparation has been ingested [12,50]

In terms of products, Propionyl-L-Carnitine is commonly included in dietary supplements, particularly those aimed at heart health, energy enhancement, and Sporternhrung

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Gamidov S.G., Ovchinnikov R.O., Popova A.P

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