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A ring of 8-15 C subunits (depending upon the species), and the subunit, rotates as protons pass through the membrane

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It is reasonable to speculate that the hypoxia microenvironment in AS lesions may serve as a trigger for immune cells, particularly neutrophils, to become activated and contribute to the pathogenesis of AS through the MAPK and HIF-1 signaling pathways

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doi: 10.1074/mcp.M400015-MCP200

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