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doi: 10.3390/nu14235003

Deficiencies in B12 or defects in methionine synthase will result in 5-methyl-THF trapping with the result being the development of megaloblastic anemia due to the block in nucleotide production and the inability of bone marrow erythroblasts to proceed through S-phase of the cell cycle

doi: 10.1007/978-1-4939-8751-1_7

doi: 10.1097/MD.0000000000032771 55 DasJKFeltyQPoppitiRJacksonRMRoyD

The implications of this finding overshadowed the importance of mitochondria for tumor growth for a long time
