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Interestingly, inhibition of NLRP3 inflammasome activation reversed the M1 polarization of TMAO-stimulated macrophages, suggesting that NLRP3 plays a crucial role as a proteolytic activator in TMAO-induced macrophage responses
Ilochi James
Brydges NM, et al
Arginine is a type of amino acid thats important for regulating blood flow
On the contrary, Acetyl-CoA is an activator of pyruvate carboxylase, thus promoting the TCA flux or the gluconeogenesis (Pietrocola et al., 2015)
