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For uterine fibroids, most therapeutics focus on two symptoms, bleeding management and shrinking fibroid size, which translates to a smaller pipeline

doi: 10.7326/0003-4819-147-6-200709180-00005 193

In contrast, glycine (and D-serine) can facilitate excitatory neurotransmission by serving as an obligatory co-agonist at NMDA receptors, thereby influencing receptor gating, synaptic plasticity, and downstream signaling in cortical and hippocampal circuits

However, the results did not meet the primary endpoints with sufficient statistical significance, and the program was not pursued further

[DOI] [PubMed] [Google Scholar] 42.Zhao Y., Huang H., Lv N., Huang C., Chen H., Xing H., Guo C., Li N., Zhao D., Chen X., et al