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Description
In inducing apoptosis in human lymphoma cells, Sag has shown to selectively activate programmed cell death in sensitive cell lines, providing evidence for its potential as a new inducer of lymphoma cell apoptosis
Stepwise one-electron reductions of O 2 yield O 2 , which yields hydrogen peroxide (H 2 O 2 ) and finally converts to OH ( 2 O 2 produced from O 2 can be detoxified by mitochondrial or cytoplasmic catalase or can yield the highly diffusible H 2 O 2
To enhance the cell permeability of RT, we converted the carboxylic acid groups to acetoxymethyl (AM) esters, which are readily hydrolysed by esterases to regenerate RT inside cells
doi:10.1046/j.1365-2958.2001.02283.x
autoimmune conditions attack the specific mitochondrial cells
