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Data demonstrate that patients treated with NSAIDs were more likely to die in the first year following a myocardial infarction compared to those not treated with NSAIDs

Skin cells are very susceptible to telomere shortening and oxidative stress

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For acute shoulder injuries causing significant pain, split dosing at 0.25mg twice daily may produce better results than 0.5mg once daily despite the same total amount

For instance, a study by Grace et al., on lambs receiving a single 2 mg subcutaneous B12 injection demonstrated significant increases in serum and liver B12 concentrations for up to 24 days compared to untreated animals (2)