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A single, intravenous or intranasal sub-anesthetic dose of ketamine, a non-competitive NMDA glutamate receptor channel blocker, produces a rapid onset of antidepressant response that can last several days in the majority of treatment resistant unipolar and bipolar depressed patients participating in a growing number of clinical trials 148150
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Koepp MJ, Edwards M, Collins J, et al
The Making of a West Indian Island: Jamaica Kincaids Representation of Antigua
Wing, A
