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In experimental studies, formation of complexes of cellular antigen with antibody resulted in activation of dendritic cells, facilitation of cross-presentation of antigens to tumor-specific CD 8 + T cells and inhibition of tumor growth Fc receptor-targeted antigen uptake was shown to initiate cross-presentation pathways as an immune regulatory mechanism for effective tumor immunity

1ch) that confer different biophysical properties including sensitivity to Mg 2+ block, sensitivity to allosteric modulators, deactivation time course, single channel conductance, channel open probability for an agonist-bound receptor, and agonist potency (Fig

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