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demonstrated that a marked increase in the expression of p62, LC3, and Beclin-1 was related with radiation therapy in glioblastoma biopsy samples, whereas LC3 and p62 expression was associated with a poorer overall survival, and LC3 was associated with the methylation in the promoter of O 6 -methylyguanine-DNA methyltransferase (MGMT) and telomerase reverse transcriptase (TERT)

Two-way within-subject ANOVA was performed, and the interaction of drug with time was analyzed by comparing data acquired after treatment for 1 month (visit 2), 2 months (visit 3), and 3 months (visit 4) relative to baseline (visit 1)