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Individual components of the apoptotic machinery involved in regulation of ER stress-mediated cell death include Bax, Bak, Bim, or PUMA (p53 upregulated modulator of apoptosis), as well as the transcription factor CHOP (C/EBP homologous protein)-dependent pathway [89]
Pd-L1 is a novel direct target of hif-1alpha, and its blockade under hypoxia enhanced mdsc-mediated T cell activation
Devalia, for the British Committee for Standards in Haematology
Sci Adv (2017) 3(6):e1602025.10.1126/sciadv.1602025 114 TilbrookPAIngleyEWilliamsJHHibbsMLKlinkenSP
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