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G protein-coupled receptor-G-protein -subunit signaling mediates renal dysfunction and fibrosis in heart failure

We performed further refinement from literature and by using the human metabolic networks in the HumanCyc database (Trupp et al, 2010) and Recon3D (Brunk et al, 2018)

Then we further detected HIF-1 expression and localization in 30 UC tissues and 20 healthy colon tissues with IHC assay
doi: 10.1016/s0895-7061(02)03253-3
