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Conclusions: In patients with PMR undergoing cardiac surgery RV-PA coupling may identify a more compromised group of patients and it is related to clinical outcomes in the very short-term after surgery

Decreased adipose lipid turnover associates with cardiometabolic risk and the metabolic syndrome
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Single-cell RNA sequencing and spatial transcriptomics are novel approaches that provide deeper insights into the cellular heterogeneity in DPN pathogenesis

Comorbid conditions, such as diabetes and chronic kidney disease, amplify ketamines neurotoxicity by increasing oxidative stress and impairing drug metabolism
