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1 ), with persistence of defects ( Tables 1 and 2 ), continuous fistula leakage ( Table 3 ), sphincter failure ( Table 4 ) and significant mortality rate ( Table 5 )

Alternative protocols include: Daily low-dose: 750 mcg daily for 3 months, then cycling one month off

Teriparatide is already used clinically in some of these cases, and the preclinical evidence for BPC-157 specifically addressed bone defects that failed to heal in control animals

Peptide-based thermosensitive hydrogels have been extensively reviewed elsewhere

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