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Renal insufficiency : People with renal insufficiency should be cautious with L-carnitine supplementation, as this could lead to an accumulation of the substance in the blood
Diabetes Res Clin Pract 1991;14:191-5

GCDH can be controlled nutritionally and supplementation includes L-carnitine to avoid secondary carnitine depletion [8487]

For heart-related questions, the underlying condition matters more than the supplement itself
