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Much of Noopept cognitive effect may be mediated through its metabolite cycloprolylglycine (cPG), which concentrates preferentially in the hippocampus and has been shown to reduce hippocampal cell death, increase BDNF mRNA, and modulate inflammatory cytokine expression
Hepatology 63 , 18281841 (2016)
It also acts as an inherent inhibitor of tissue inflammation instigated by MSU crystal-induced monocyte activation (21)
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When ROS are generated, antioxidants in the mitochondria maintain redox homeostasis under normal conditions
