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"Combination therapy with doxazosin and finasteride for benign prostatic hyperplasia in patients with lower urinary tract symptoms and a baseline total prostate volume of 25 ml or greater"

There is some limited support for other effects, but more research is needed

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It has been established that all GSTs exist as dimeric proteins and have serine in the active site, however, DHARs and Lambda class GSTs are monomeric, and possess catalytic cysteine in active site (Wagner et al., 2002

In conclusion, we revealed novel structurefunction relationships of glutaredoxins, gained insights regarding the enzymatic conversion of glutathione- and non-glutathione disulfide substrates, and identified two distinct substrate interaction sites that include a scaffold residue and the conserved dual activator Lys105 in ScGrx7 and Lys26 in PfGrx