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This occurs through selective oxidation on FASN and transcriptional inhibition on lipogenic genes, leading to decreased lipogenesis and fibrosis

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They can occur because of an underlying health problem, but more often, they are due to age-related changes

Adaptation to a 96-well plate format enabled high-throughput analysis of sulfenic acid in cells and this platform was used to screen a curated inhibitor library, targeting major families of the human kinome, as potential modulators of cysteinyl oxidation