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Skp alleviates the ferroptosis in diabetic kidney disease through suppression of hif-1alpha/ho-1 pathway based on network pharmacology analysis and experimental validation

Hyperglycemia-driven neuroinflammation compromises BBB leading to memory loss in both diabetes mellitus (DM) type 1 and type 2 mouse models

Glutathione levels decline with age, chronic illness, high oxidative load (alcohol, medications, pollution, chronic stress), and acute illness

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[DOI] [PubMed] [Google Scholar] 158.Lekakis J, Abraham P, Balbarini A, Blann A, Boulanger CM, Cockcroft J, Cosentino F, Deanfield J, Gallino A, Ikonomidis I, Kremastinos D, Landmesser U, Protogerou A, Stefanadis C, Tousoulis D, Vassalli G, Vink H, Werner N, Wilkinson I, and Vlachopoulos C
