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NQO1 and NRF2 may be valuable biomarkers for early diagnosis, prognostic, and therapeutic strategies in patients with cervical and endometrial carcinomas, in line with additional research showing that NRF2 overexpression was significantly associated with high-grade and advanced-stage endometrial and ovarian carcinomas (Cho et al., 2017

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For instance, curcumin-loaded tetrahedral framework nucleic acids were synthesized to deliver curcumin, which exhibited better drug stability, biocompatibility, ease of uptake, higher tissue utilization and a better anti-inflammatory effect when compared to free curcumin in vitro and in vivo