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The Wnt/-catenin signaling pathway plays a crucial role here

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Via the catalytic activity of a broad superfamily of phase II detoxification enzymes, the Glutathione STransferases (GSTs), glutathione is covalently conjugated to electrophilic xenobiotics and endogenous reactive intermediates

How It Is Studied In laboratory research, 5-Amino-1MQ is typically applied to cultured cell lines to assess changes in NNMT enzymatic activity via methyltransferase assays

Glutathione: New roles inredox signaling for an old antioxidant