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Glutathione-Depleting Nanomedicines for Synergistic Cancer Therapy

Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation

Stimuli-Responsive Systems Stimuli-responsive systems release drugs in response to environmental cues, such as low pH (~6.0 in inflamed joints), high ROS, or enzyme activity

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GC91083 Tiopronin-Cysteine Disulfide A metabolite of tiopronin GC30237 Verdiperstat (AZD3241) AZD3241 Verdiperstat (AZD3241) (AZD3241) is a selective, irreversible and orally active myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.