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Identify and manage the underlying root cause for B12 deficiency anemia

In case of high-risk patients or new-onset subclinical neurographic changes, starting slowly or lowering the speed and the dose of infusion respectively, might help avoiding the risk of progression of the PN and even improve the PN (Rispoli et al

There is an increased risk for diabetic retinopathy complications in patients with a history of diabetic retinopathy at baseline compared to patients without a known history of diabetic retinopathy

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The study emphasized that both the fatty acid chain length and the site of lipid attachment critically affect the pharmacokinetic and pharmacodynamic profiles of peptide drugs [80]