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Association between metformin dose and vitamin B12 deficiency in patients with type 2 diabetes

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The recommended daily intake of vitamin B12 varies according to age, physiological status, and individual health circumstances

The reason why homocysteine is dangerous is because it damages cells and tissues of the arteries, triggers inflammatory reactions and enables cholesterol oxidation, which contributes to the build-up of atherosclerotic plaques the main culprits in cardiovascular disease (Kumar et al., 2017)