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In addition, a foreign in vitro experimental study on human glioma A172 cells found that metformin increased the expression of AMPK/pAMPK/Bax protein and decreased the expression of mTOR/Bcl-2 protein in a dose and time-dependent manner, thereby inhibiting the proliferation and apoptosis of A172 cells
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10.1007/s00204-015-1486-9 64 KoparalM.KurtE.AltuntasE

Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinsons disease

Synergistic Effect of All-Trans-Retinal and Triptolide Encapsulated in an Inflammation-Targeted Nanoparticle on Collagen-Induced Arthritis in Mice
