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(ii) GC1 has a higher Km (~5 mM) for glutamate/H+, similar to the levels measured in intact mitochondria from the liver and kidney, whereas GC2 has a markedly lower Km (~0.26 mM) and shows low expression in many tissues [39]

Therefore, carnitine/acylcarnitine not only play roles in muscle energy metabolism but also participate in the whole-body energy balance and fatigue perception by affecting neuromuscular signaling, underscoring the potential importance of carnitine in exercise physiology, exercise recovery and performance improvement

Arredondo, M

Glutamine uptake is enhanced in activated lymphocytes