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Because this number reflects the disease-positive cohort rather than the disease-negative cohort, it cannot represent the expected number of false-positive test results

Phagosomal maturation involves several RAB GTPases (a family of small GTPases) that mediate the fusion of vesicles containing oxidants and other toxic elements with the phagosome to form the mature phagolysosome (Figure 1) [24]

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