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We also observed decreased pan-acetylation of histones H3 and H4 in Ovcar8-CCNE1 tumours in mice treated with the IDH1 inhibitor (Fig

2013;3(11):e95e95

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It potently protects sperm mitochondria against electron transport chain-induced ROS through some mechanisms including radical scavenging, iron ions chelating, and increasing expression of mitochondrial antioxidants such as superoxide dismutase (SOD), glutathione (GSH), catalase (CAT), and glutathione peroxidase (GPx), maintains sperm mitochondrial membrane and DNA integrity, and finally modulates the sperm cell apoptotic signaling

1D,E), indicating that changes in AC content in the heart could determine changes in the AC profile in plasma