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Additionally, in hormone receptor-positive breast cancer, the most common modification in the PI3K/AKT/mTOR signaling pathway is the loss of PTEN [88], which is a pivotal regulator in the PI3K/AKT/mTOR pathway involved in cell growth and survival, cell migration, and genomic stability [89]

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doi: 10.1038/s41591-020-1051-9 24 Donoso-NavarroE.GmezI

[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Tsai K.F., Chen Y.L., Chiou T.T.Y., Chu T.H., Li L.C., Ng H.Y., Lee W.C., Lee C.T

Belanche A, Palma-Hidalgo JM, Nejjam I, Jimnez E, Martn-Garca AI, Yez-Ruiz DR
