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Methylglyoxal at metronomic doses sensitizes breast cancer cells to doxorubicin and cisplatin causing synergistic induction of programmed cell death and inhibition of stemness

Thus, the intracellular environment not only provides a physical barrier but also promotes antibiotic tolerance

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Experimental animals The Wistar rats and Zebra fish ( Danio rerio ) used in this study were obtained from the Department of Pharmacology, Faculty of Pharmacy, MS Ramaiah University of Applied Sciences, Bengaluru, India

Sermorelin was previously FDA-approved (as Geref) for diagnostic purposes but has been discontinued by its manufacturer