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Within the human body, it plays a role in: DNA expression Embryo development Cellular energy production Neurotransmitter synthesis Hormone production and metabolism Inflammation and immune responses Conversion of the amino acid called homocysteine into another amino acid called methionine

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P., et al., Nicotinamide Adenine Dinucleotide Phosphate OxidaseMediated Redox Signaling and Vascular Remodeling by 16Hydroxyestrone in Human Pulmonary Artery Cells: Implications in Pulmonary Arterial Hypertension, Hypertension 68, no

Special Situations TOXIC APPEARANCE Toxic-appearing infants and children are pale or cyanotic, lethargic or inconsolably irritable