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Extensive evidence has been obtained that class III peroxidases are one of the mechanisms for launching oxidative defense in plants, but no oxidant for these enzymes has been identified in any plant parasite systems

Importantly, protein adducts on mitochondria are most critical for toxicity because they trigger initial oxidative stress, which is amplified through a mitogen-activated protein (MAP) kinase cascade with the ultimate activation of c-jun N-terminal kinase (JNK)

Additionally, it plays a part in the creation of glutathione, your bodys master antioxidant

Evidence for a direct link between PAD4-mediated citrullination and the oxidative burst in human neutrophils

doi: 10.1016/s0065-230x(08)60848-9