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Middle-aged adults (30-60) Represent the primary target population with standard dosing protocols directly applicable

Overactive bladder (OAB) is defined as a symptom complex characterized by urinary urgency, usually accompanied by frequency and nocturia, but with or without urgency urinary incontinence, in the absence of causative infection or pathologic condition 2,3

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Chronic alcohol use can by itself damage the intestinal barrier and increases plasma LPS levels, both of which normalized after a longer period of abstinence (145, 148)

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