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Despite the large number of epigenetic changes found in sensitized USCs, only a few DEGs were observed when USCs were cultured under stem cell-promoting conditions, suggesting that the epigenetic changes we found may have a greater impact on gene expression upon cell differentiation

Pathophysiological Considerations 3.1

In adult brain, the synthesis rate decreases significantly [32, 42]

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The 2012 fungal meningitis outbreak caused by contaminated compounded medications from a Massachusetts pharmacy remains a landmark case showing catastrophic consequences of poor sterile compounding practices