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Description
11 , e2201240 (2022)

Ceruloplasmin: This protein is decreased in Wilsons disease, cirrhosis, and many causes of chronic hepatitis, but may be increased by inflammation, cholestasis, hemochromatosis, pregnancy, and estrogen therapy

Zonulin promoted T follicular helper (Tfh) cell differentiation and suppressed T follicular regulatory (Tfr) cell functionthrough mechanisms yet to be fully elucidatedleading to an increased Tfh/Tfr ratio
L., Mani S

These latter data confirm and extend results by Nikolaeva, et al
