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Interestingly, no significant differences were found in creatine kinase, IL-6, or TNF-alpha, suggesting that a larger dose of curcumin and a greater frequency of consumption on recovery days (post-exercise) may be needed to have more significant effects (251)

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It is characterized by an imbalance between excessive production of reactive oxygen species (ROS) and weakened antioxidant defenses, leading to persistent oxidative stress (Maes, 2009

doi: 10.1007/s15010-025-02568-y

Notably, tau protein lactylation at K677 initiates ferroautophagy and ferroptosis through the MAPK pathway, leading to microglial activation and neuroinflammation [82]
