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Although this notion remains to be clarified, previous studies have shown that the basal level of myocardial autophagy is much higher in FVB/N mice (1-fold increases in autophagic flux by 6 h of chloroquine at a dose of 50 mg/kg, i.p.) compared to C57BL/6J mice (0.5-fold increases in autophagic flux by 6 h of chloroquine at a dose of 50 mg/kg, i.p