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This ongoing inflammatory fire drives many of the debilitating, systemic symptoms patients experience months or even years after the initial acute infection has seemingly cleared

Br J Pharmacol 135(2):520536 Hadzic T, Li L, Cheng N, Walsh SA, Spitz DR, Knudson CM (2005) The role of low molecular weight thiols in T lymphocyte proliferation and IL-2 secretion

Several works have shown that the accumulation of fat is toxic per se and causes lipo-toxicity [134]

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Increased Plasma Methylglyoxal Level, Inflammation, and Vascular Endothelial Dysfunction in Diabetic Nephropathy