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Moreover, excess iron could promote the formation of reactive oxygen species (ROS), which can lead to oxidative stress and DNA damage, with cytokine-regulated inflammatory pathways and a central contribution from innate immune cells in the tumor microenvironment (360, 361)

doi: 10.1111/j.1365-2672.2012.05344.x 93 DhakalRBajpaiVKBaekKH

Gclc siRNAs: GCGAUGAGGUGGAAUACAU, UAACAGACUUUGAGAACUC, UGGCAGACAAUGAGAUUUA, CCAUCUCCAUUUAUAGAAA
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