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El-Sheikh AAK, Morsy MA, Mahmoud MM, Rifaai RA, Abdelrahman AM (2012) Effect of coenzyme-Q10 on doxorubicin-induced nephrotoxicity in rats [Article]

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IMC and FMC suppress host TMA and TMAO levels for sustained periods, with limited systemic exposure and without notable toxicity, at inhibitory efficiencies of about 10,000 times that of DMB ( in vivo rate of thrombus formation without increased bleeding time ( in vivo TF expression and thrombogenicity ( In summary, targeting the inhibition of TMA lyase could reduce plasma TMAO levels and play a protective role in AS

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Endocr J 2016 Jul 16

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These effects, described in animal models, were not generally observed in humans

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