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In humans, melatonin accelerates falling asleep, reduces the number of nighttime awakenings, prolongs the total duration of sleep, and improves its quality. SLEEP REGULATION PROCESSES Two processes participate in sleep regulation: homeostatic and circadian

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Secondary outcomes are the safety of SAMe administration (incidence of serious adverse events), change from baseline in cognitive performance (as measured by the Repeatable Battery for the Assessment of Neuropsychological Status), and epigenetic changes in DNA methylation

This narrative review provides practical guidelines for clinicians, nutritionists, trainers, sports scientists, and athletes to design personalized supplementation strategies that address common nutritional shortfalls, enhance performance, and serve as a foundation for future research in vegan sports nutrition