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25,26 Two pairs of JAM-A dimers from apposing cell surfaces ensure intercellular interaction through the immunoglobulin-like domain, while their PDZ-binding motif at the C-terminus allows TJ regulation by myriad scaffolding proteins
But few, if any, prove their hype or are supported by real science
Maintenance: Once every 1-2 weeks
111 Additionally, NETs can induce apoptosis in epithelial cells, compromising the integrity of the intestinal barrier and exacerbating intestinal inflammation in IBD mouse models
T., Sadoshima, J., and Li, H
