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Prior to docking, all water molecules were removed from the AcvB C structure

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As a principal transcriptional regulator of intestinal iron transporters, HIF-2 plays a crucial role in maintaining systemic iron balance after birth ( in vitro ( Beyond iron transport, HIF signaling also shapes IBD through cell-typespecific immune programs, which helps reconcile seemingly conflicting findings across models

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Journal of Thoracic and Cardiovascular Surgery 169(3):710-715.e7, 2025

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