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In addition, ferroptosis-induced changes in the TME can suppress the activity of APCs, including dendritic cells, hindering their ability to present tumor antigens to T cells, increasing the survival advantage of cancer cells [123]
The chemistry of the molecule, and its participation in the reactions the literature describes, depends on this exact sequence
Koch et al., 2004)
Excessive proliferation of VSMCs leads to arterial wall thickening and lumen narrowing, increasing peripheral vascular resistance and cardiac afterload
10.1016/j.lfs.2005.09.040 228
