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Blood 98:568a, 2001

Furthermore, tumor necrosis factor- (TNF) and prostaglandins (PGs), released from astrocytes under traumatic events, can reactivate their calcium signaling, and can cause increased glutamate release (Bezzi et al., Reactive astrocytes are also involved in the pathogenesis of other neuronal disorders

10.1016/j.drup.2012.02.001 Drug Resist

In addition, the acceptance of coffee enemas among patients also needs to be studied

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